Relationship between myostatin, musclin, nutritional status, and functionality in older Colombian community-dwelling adults: A cross-sectional study.

Nancy Marulanda-Díaz, Alejandro Estrada-Restrepo, Andrés F Milán, Raul Narvaez-Sanchez, Juan C Calderón, Nubia A Giraldo-Giraldo

Human Nutrition Research Group - GIANH, School of Nutrition and Dietetics, University of Antioquia, Medellín, Colombia; Physiology and Biochemistry Research Group - PHYSIS, Faculty of Medicine, University of Antioquia, Medellín, Colombia. · pubmed

Paper

Abstract

Aging-associated body composition changes lead to a decrease in muscle mass and strength, affecting the functionality of older adults. Myostatin and musclin are myokines that regulate muscle metabolism and may modulate muscle changes during aging. Our objective was to determine the relationship between myostatin, musclin, and nutritional status with physical functionality in older adults.

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Research summary

The paper claims that myostatin and musclin levels, along with nutritional status, are related to physical functionality in older adults. This research addresses factors that influence muscle metabolism and functionality, which are critical aspects of aging and longevity.

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