Systematic review of interventions for pre-frail and frail older adults: Evidence from clinical trials on frailty levels.

Andressa C da Silva Sobrinho, Reisa Cristiane de Paula Venancio, Guilherme da Silva Rodrigues, Mariana Porto, Layana Liss Schwenger, Letícia Fernanda Belo, Luana K Ferreira, Carlos Roberto Bueno Júnior, Grace Angelica de Oliveira Gomes

Department of Internal Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. Electronic address: [email protected]. · pubmed

Paper

Abstract

The increasing global longevity underscores the necessity of effective interventions for older adults. Pre-frailty and frailty affect 54.1 % and 26.3 % of the elderly population, respectively, leading to adverse physical and cognitive outcomes. This study systematically reviewed the effectiveness of interventions targeting robust, pre-frail, and frail older adults in randomized controlled trials, analyzing frailty levels both collectively and individually.

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Research summary

The paper claims that various interventions can effectively reduce frailty levels in older adults. The focus on interventions for pre-frail and frail older adults addresses critical aspects of aging and longevity, aiming to improve health outcomes and potentially extend the functional lifespan of this population.

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