Crocin extends lifespan by mitigating oxidative stress and regulating lipid metabolism through the DAF-16/FOXO pathway.

Ai-Pei Li, Dan Li, Xin Tan, Rui Xu, Lin-Xi Mao, Juan-Juan Kang, Sheng-Hong Li, Yan Liu

College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P. R. China.College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P. R. China. · pubmed

Paper

Abstract

Aging represents a significant global challenge characterized by persistent oxidative stress and dysregulated lipid metabolism. Crocin, the primary bioactive constituent of saffron (

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Crocin extends lifespan by mitigating oxidative stress and regulating lipid metabolism through the DAF-16/FOXO pathway. The paper addresses mechanisms that may directly influence aging processes, specifically oxidative stress and lipid metabolism, which are critical factors in longevity research.

Author of this paper? Send a correction.