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RESEARCH PAPER / 2025-04-19

Exploring the impact of Gastrodin on brain aging in mice: Unraveling mechanisms through network pharmacology.

Jiecai Li, Rui Yuan, Sheng'an Zheng, Ying Wang, Julian Miao

School of Pharmacy, Dali University, Dali, Yunnan Province, 671000, China. · pubmed

Abstract

With the intensification of global aging, slowing down the aging process has become a topic of significant interest. Brain aging, as one of the prominent changes in the aging process, urgently requires the exploration of new therapeutic methods to delay its progression. Gastrodia, a traditional Chinese medicine, has been widely recognized for its medicinal value, particularly in its pronounced neuroprotective effects. Although previous studies have demonstrated the protective effects of Gastrodin (GAS), an active compound in Gastrodia, on the mouse nervous system, its underlying mechanisms remain unclear.

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Research summary

The paper investigates the neuroprotective effects of Gastrodin on brain aging in mice. This research is relevant as it explores potential therapeutic methods to slow down brain aging, addressing a key aspect of the aging process.

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