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RESEARCH PAPER / 2025-04-13

Lycium barbarum polysaccharide ameliorates corticosterone-induced cognition decline with modulation of CRHR1.

Xiao-Xiao Shi, Xiao-Feng Tian, Bin He, Su-Na Liu, Cui-Ge Shi, Ying Shi, Yi-Shu Yang

Department of Clinical Laboratory, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.Department of Clinical Laboratory, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China. · pubmed

Abstract

Lycium barbarum polysaccharide (LBP) has anti-inflammatory, anti-oxidation and anti-aging properties, but the mechanism of LBP on stress-induced cognitive dysfunction caused by elevated GC level is still unclear.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Lycium barbarum polysaccharide (LBP) may improve cognitive function by modulating CRHR1 in the context of stress-induced cognitive decline. The study addresses a potential mechanism that could contribute to understanding and mitigating cognitive decline associated with aging.

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