Isoflavone intake is associated with longitudinal changes in hippocampal volume, but not total grey matter volume, in Japanese middle-aged and older community dwellers.

Mariko Nakamoto, Yukiko Nishita, Chikako Tange, Shu Zhang, Hiroshi Shimokata, Tohru Sakai, Rei Otsuka

Department of Public Health and Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto-cho, Tokushima city, Tokushima, 770-8503, Japan. [email protected] of Public Health and Applied Nutrition, Institute of Biomedical Sciences, Tokushima University Graduate School, 3-18-15 Kuramoto-cho, Tokushima city, Tokushima, 770-8503, Japan. [email protected]. · pubmed

Paper

Abstract

This study aimed to clarify the associations between isoflavone intake and the volume changes of brain regions, specifically the hippocampus and total grey matter (TGM), over 10 years in Japanese middle-aged and older community dwellers.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Isoflavone intake is associated with changes in hippocampal volume over time in older adults. The study explores dietary factors that may influence brain health and aging, which is pertinent to understanding longevity and age-related cognitive decline.

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