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RESEARCH PAPER / 2025-04-09

Association between systemic immune inflammation index and serum testosterone and free testosterone in middle-aged and elderly men.

Liang Su, Si-Zheng Zhang, Hao-Yang Cheng, Zheng-Yang Zhou, Qi Zhang, Jie Wu, Yong-Zheng Jiao

Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China. · pubmed

Abstract

Chronic inflammation is a pervasive feature of aging and may be associated with testosterone in middle-aged and older men. Systemic immune-inflammation index (SII) is a novel inflammatory biomarker. We aimed to assess the association between SII and serum testosterone and free testosterone (FT) in middle-aged and older men.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that there is an association between systemic immune inflammation index and serum testosterone levels in middle-aged and elderly men. This research is relevant as it explores the relationship between inflammation and testosterone, which may have implications for understanding age-related hormonal changes and their potential impact on longevity.

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