Maternal telomere length and oxidative stress in pregnancy: cross-sectional analysis with an exploratory examination of systemic inflammation.

Laura Etzel, Qiaofeng Ye, Abner T Apsley, Chris Chiaro, Lauren E Petri, John Kozlosky, Cathi Propper, Roger Mills-Koonce, Sarah J Short, Patricia Garrett-Peters, Idan Shalev

Social Science Research Institute, Duke University, Durham, NC, USA.Social Science Research Institute, Duke University, Durham, NC, USA. · pubmed

Paper

Abstract

Telomere length (TL) is a marker of cellular aging associated with risk for age-related diseases and is known to be influenced by various factors, including oxidative stress and inflammation, in the contexts of stress and aging. The physiological demands of pregnancy may impact maternal TL, though research in this area is sparse. We tested oxidative stress and explored inflammation as predictors of maternal TL in a sample of women with normative pregnancies.

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Research summary

The paper investigates the relationship between oxidative stress, inflammation, and maternal telomere length during pregnancy. This research is relevant as it explores factors that may influence cellular aging, which is a key aspect of longevity and age-related health.

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