Increased Brain Age Among Psychiatrically Healthy Adults Exposed to Childhood Trauma.
Abstract
Adults with childhood trauma exposure may exhibit brain changes typically associated with aging and neurodegeneration (e.g., reduced tissue volume or integrity) to a greater degree than their unexposed counterparts, suggesting accelerated brain aging. Machine learning methods that predict a person's age based on their magnetic resonance imaging (MRI) brain scan may be useful for investigating aberrant brain aging following childhood trauma exposure. Emerging evidence indicates altered brain aging in adolescents with childhood trauma exposure; however, this association has not been examined in healthy adults.
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Research summary
The paper claims that adults with childhood trauma exhibit brain changes indicative of accelerated aging. This research is relevant as it explores the relationship between childhood trauma and brain aging, potentially addressing underlying mechanisms that contribute to age-related cognitive decline.
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