Adipogenic Effect of Magnolol in Primary Human Pre-Adipocytes With Potential Skin Health and Volumizing Effect.

Alan D Widgerow, Nava Dayan, Mary E Ziegler, Faiza Shafiq

Division Chief Research, Professor Plastic Surgery, Center for Tissue Engineering, University of California, Irvine, California, USA. · pubmed

Paper

Abstract

Aging is associated with fat atrophy and fibrosis with loss of adipocyte differentiation from preadipocytes. New approaches to this loss involve agents that can renew the proliferative and differentiative capacities of preadipocytes with the aim of creating new healthy adipose tissue that secrete adipokines that positively impact on skin health.

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Research summary

The paper claims that Magnolol can enhance the differentiation of pre-adipocytes into adipocytes, potentially improving skin health. This research is relevant as it addresses the loss of adipose tissue and its implications for aging and skin health, which are associated with age-related changes.

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