Cognitive Training and Enrichment Modulates Neural Plasticity and Enhances Cognitive Reserve in Aging Rats.

JenishaChris Stephen, Ronyson Kharkongor, UlfathTasneem Khan, Muniraj Kathirvel, Rameshkumar Radhakrishnan

Department of Anatomy, Dr. Arcot Lakshmanasamy Mudaliar Post Graduate Institute of Basic Medical Sciences, University of Madras, Chennai, India.Department of Anatomy, Dr. Arcot Lakshmanasamy Mudaliar Post Graduate Institute of Basic Medical Sciences, University of Madras, Chennai, India. · pubmed

Paper

Abstract

Cognitive decline in non-pathological aging is widely prevalent among the aging population. The current study assessed the impact of cognitive training (Ct) with multiple modules targeting various facets of learning and memory and the additional influence of an enriched environment (Ct+ee) on hippocampal subfields of aging male rats.

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Research summary

Cognitive training and an enriched environment can enhance cognitive reserve and neural plasticity in aging rats. This study addresses cognitive decline in aging, which is a significant aspect of longevity research, focusing on interventions that may improve cognitive function as individuals age.

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