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RESEARCH PAPER / 2025-03-21

The Codonopsis pilosula water extract improves testicular inflammatory aging in D-galactose induced aging mice by modulating the CLEC7A/inflammasome pathway.

Jing Wang, Xuechan Li, Caihong Li, Lijun Liu, Zhenjuan Wang, Juan Feng

School of Public Health, Gansu University of Chinese Medicine, Lanzhou, 730000, China. Electronic address: [email protected] of Public Health, Gansu University of Chinese Medicine, Lanzhou, 730000, China. Electronic address: [email protected]. · pubmed

Abstract

Aging-induced testicular inflammation impairs male fertility. The purpose of this study was to investigate the effectiveness and mechanism of C. pilosula water extract (CPWE) in preventing testicular inflammation in D-galactose-induced aging mice.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The study claims that C. pilosula water extract can improve testicular inflammatory aging in mice. This research addresses a specific aspect of aging-related inflammation, which is relevant to understanding and potentially mitigating age-related decline in male fertility.

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