Age-related changes in the immune system and challenges for the development of age-specific vaccines.
Abstract
A better understanding of how the immune system evolves with age and how vaccines work in older people has led to increasing focus on the development of vaccines aimed specifically at older age groups. We discuss strategies used to improve vaccine immunogenicity for older adults, focusing on licensed adjuvants.
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Research summary
The paper discusses strategies to improve vaccine immunogenicity for older adults. This research is relevant as it addresses the challenges posed by age-related changes in the immune system, which is crucial for developing interventions that could enhance healthspan and potentially impact longevity.
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