Evaluation of Anti-aging Agents Using the D-Galactose-Induced Accelerated Aging Model.
Abstract
The aging population is rapidly increasing, emphasizing the importance of understanding aging mechanisms and developing effective anti-aging therapies. This chapter investigates the efficacy of novel anti-aging agents, including exosomes and boron compounds, using the D-galactose-induced accelerated aging model. Both in vitro (skin organoid models) and in vivo (rat models) systems are employed to explore cellular, molecular, and histological changes. This comprehensive analysis provides critical insights into the potential of these agents in reversing age-associated pathologies.
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Research summary
The paper investigates the efficacy of novel anti-aging agents in reversing age-associated pathologies. This research is relevant as it focuses on potential interventions that target the mechanisms of aging rather than merely addressing symptoms of age-related diseases.
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