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RESEARCH PAPER / 2025-03-18

BEETter AGING: Short-Term Dietary Nitrate Supplementation Enhances Muscle Contractile Properties in Older But Not in Young Adults.

Letizia Rasica, Marta Colosio, Alessandra Ferri, Giovanni Baldassarre, Chris Easton, Mia Burleigh, Gianluca Vernillo, Roberto Bottinelli, Mauro Marzorati, Simone Porcelli

Department of Kinesiology and Physical Education, Faculty of Arts and Science, University of Lethbridge, Lethbridge, Alberta, CANADA.Department of Kinesiology and Physical Education, Faculty of Arts and Science, University of Lethbridge, Lethbridge, Alberta, CANADA. · pubmed

Abstract

Dietary nitrate (NO3-) supplementation has been shown to improve skeletal muscle contractile function and reduce fatigue, potentially due to alterations in skeletal muscle Ca2+ handling/sensitivity. Since aging muscle can have impaired Ca2+ handling, the aim of the study was to evaluate the effects of dietary NO3- supplementation on muscle contractile properties in young and older adults.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Short-term dietary nitrate supplementation enhances muscle contractile properties in older adults. The study addresses a potential intervention to improve muscle function in aging, which is directly related to the aging process and its effects on physical capabilities.

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