Epigenetic Clocks Relate to Four Age-Related Health Outcomes Similarly across Three Countries.

Eileen M Crimmins, Belinda Hernandez, Claire Potter, Jung Ki Kim, Albert Higgins-Chen, Rose Anne Kenny, Aisling M O'Halloran, Bernadette McGuinness, Laura J Smyth, Claire Hill, Giovanni Fiorito, Jessica Faul, Amy Jayne McKnight, Cathal McCrory

Davis School of Gerontology, University of Southern California, Los Angeles, California, USA. · pubmed

Paper

Abstract

Measures of epigenetic age have been linked to life circumstances and health outcomes in older populations. The similarity of these relationships across multiple populations in well-harmonized data has not been addressed. We examine links between epigenetic age, based on currently widely used indicators and key health outcomes in the Republic of Ireland, the United States, and Northern Ireland with harmonized, nationally representative data on their populations age 50 and older.

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Research summary

The paper claims that epigenetic age is linked to health outcomes in older populations across three countries. This research is relevant as it explores the relationship between epigenetic markers and health outcomes, which may provide insights into the biological mechanisms of aging and longevity.

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