Streptococcus thermophilus CNCM I-5570 lysate counteracts the aging process in human dermal fibroblast cells by neutralizing harmful free radicals and impacting antioxidant and anti-inflammatory pathways, thus restoring their physiological functions.

Francesca Rosaria Augello, Francesca Lombardi, Alessia Ciafarone, Serena Altamura, Massimiliano Marazzato, Serena Artone, Benedetta Cinque, Paola Palumbo

Department of Life, Health & Environmental Sciences, University of L'Aquila, L'Aquila, Italy.Department of Life, Health & Environmental Sciences, University of L'Aquila, L'Aquila, Italy. · pubmed

Paper

Abstract

Previous studies have highlighted the in vitro and in vivo anti-aging potential of Streptococcus thermophilus prompting us to investigate the biomolecular mechanisms underlying its effects. We evaluated the reparative ability of S. thermophilus lysate in a hydrogen peroxide (H

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Research summary

The paper claims that Streptococcus thermophilus lysate can counteract the aging process in human dermal fibroblast cells by neutralizing free radicals and influencing antioxidant and anti-inflammatory pathways. This research is relevant as it investigates potential mechanisms that could address the biological processes associated with aging rather than merely treating age-related symptoms.

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