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RESEARCH PAPER / 2025-03-13

The association between gut microbiota and accelerated aging and frailty: a Mendelian randomization study.

Zhiliang Yan, Guoyu Guan, Hanqi Jia, Hanyu Li, Sangdan Zhuoga, Songbai Zheng

Department of Gastroenterology, Huadong Hospital, Fudan University, Shanghai, China.Department of Gastroenterology, Huadong Hospital, Fudan University, Shanghai, China. · pubmed

Abstract

The recent observational studies have unveiled the correlation between the composition and dynamic alterations of the gut microbiome and aging; however, the causal relationship remains uncertain.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that there is a causal relationship between gut microbiota and accelerated aging and frailty. This research is relevant as it explores potential root causes of aging through the lens of gut microbiome composition, which could have implications for longevity and age-related health.

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