Association of α-Klotho with anti-aging effects of Ganoderma lucidum in animal models.

Xiaojing Liu, Jiamin Zhao, Jia Liu, Yan Huang, Wei Deng, Luwen Yan, Ming Cui, Xinhua Pan, Huiwen Xiao, Xingzhong Liu

State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, 94 Weijin Road, Tianjin, 300071, China.State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Molecular Microbiology and Technology of the Ministry of Education, Department of Microbiology, College of Life Sciences, Nankai University, 94 Weijin Road, Tianjin, 300071, China. · pubmed

Paper

Abstract

Aging is a complex, universal process characterized by structural and functional decline across multiple organs. Ganoderma lucidum (G. lucidum), a renowned traditional Chinese medicinal fungus, has long been recognized for its anti-aging properties. However, the underlying mechanisms remain incompletely understood.

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Research summary

The paper claims that α-Klotho mediates the anti-aging effects of Ganoderma lucidum in animal models. This research is relevant as it explores potential mechanisms underlying aging and longevity, focusing on a natural compound's effects on biological aging processes.

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