The relationship between telomere length and aging-related diseases.

Xuanqi Huang, Leyi Huang, Jiaweng Lu, Lijuan Cheng, Du Wu, Linmeng Li, Shuting Zhang, Xinyue Lai, Lu Xu

Hangzhou Normal University School of Nursing, Hangzhou, China.Hangzhou Normal University School of Nursing, Hangzhou, China. · pubmed

Paper

Abstract

The intensifying global phenomenon of an aging population has spurred a heightened emphasis on studies on aging and disorders associated with aging. Cellular senescence and aging are known to be caused by telomere shortening. Telomere length (TL) has emerged as a biomarker under intense scrutiny, and its widespread use in investigations of diseases tied to advancing age. This review summarizes the current knowledge of the association between telomeres and aging-related diseases, explores the important contribution of dysfunctional telomeres to the development and progression of these diseases, and aims to provide valuable insights for the development of novel therapeutic strategies.

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Research summary

Telomere length is associated with the development and progression of aging-related diseases. The paper addresses the role of telomeres as a biomarker for aging and their potential contribution to understanding the root causes of aging-related diseases, which is pertinent to longevity research.

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