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RESEARCH PAPER / 2025-03-05

Bariatric surgery reverses morbid obesity-induced changes in the composition of circulating immune cells-a prospective cohort study.

Annick Elianna Taselaar, Leontine Henriëtte Wijngaarden, René Alexander Klaassen, Erwin van der Harst, Martin Dunkelgrun, Tjallingius Martijn Kuijper, Gisela Ambagtsheer, Tessa Hendriks, Ron Wilhelmus Frederik de Bruin, Nicolle Helena Renier Litjens

Department of Surgery, Erasmus MC, Erasmus MC Transplant Institute, University Medical Center, Rotterdam, Netherlands; Department of Surgery, Maasstad Hospital, Rotterdam, Netherlands. Electronic address: [email protected] of Surgery, Erasmus MC, Erasmus MC Transplant Institute, University Medical Center, Rotterdam, Netherlands; Department of Surgery, Maasstad Hospital, Rotterdam, Netherlands. Electronic address: [email protected]. · pubmed

Abstract

Morbid obesity is associated with aging of the immune system, a phenomenon known as "inflammaging," characterized by increased numbers of various immune cell subsets.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

Bariatric surgery can reverse changes in the composition of circulating immune cells associated with morbid obesity. This study addresses the immune system's aging process, which is a key aspect of longevity research.

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