The Inner Ear and Aging Brain: A Cross-Sectional Study of Vestibular Function and Morphometric Variations in the Entorhinal and Trans-Entorhinal Cortex.

Claire J Vania, Dominic Padova, J Tilak Ratnanather, Yuri Agrawal

Department of Biomedical Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, MD, USA. [email protected]. · pubmed

Paper

Abstract

While the vestibular system is crucial for balance, posture, and stable vision, emerging evidence connects vestibular loss in older adults to spatial cognitive deficits. However, the specific neural pathways remain unclear. This study examines morphometric changes in the entorhinal cortex (ERC) and trans-entorhinal cortex (TEC), key regions in the vestibular spatial cognitive network, with vestibular function.

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Research summary

The study investigates the relationship between vestibular function and morphometric changes in the entorhinal and trans-entorhinal cortex in older adults. This research is relevant as it explores potential neural mechanisms linking vestibular loss to cognitive deficits in aging, which could inform strategies for addressing age-related cognitive decline.

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