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RESEARCH PAPER / 2025-02-17

Protein supplementation alone or combined with exercise for sarcopenia and physical frailty: A systematic review and meta-analysis of randomized controlled trials.

Yoshihiro Yoshimura, Ayaka Matsumoto, Tatsuro Inoue, Masatsugu Okamura, Masafumi Kuzuya

Center for Sarcopenia and Malnutrition Research, Kumamoto Rehabilitation Hospital, Kumamoto, Japan. Electronic address: [email protected] for Sarcopenia and Malnutrition Research, Kumamoto Rehabilitation Hospital, Kumamoto, Japan. Electronic address: [email protected]. · pubmed

Abstract

Sarcopenia and physical frailty are age-related syndromes characterized by progressive loss of muscle mass and function, significantly impacting mortality and quality of life in older adults. This systematic review evaluated the effectiveness of protein supplementation interventions for these conditions.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that protein supplementation can improve outcomes related to sarcopenia and physical frailty in older adults. This research is relevant as it addresses interventions that may mitigate age-related decline in muscle mass and function, which are critical factors in longevity and quality of life for the aging population.

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