DNA methylation-based telomere length is more strongly associated with long-term all-cause mortality than quantitative polymerase chain reaction-based telomere length among middle-aged and older hypertensive adults.

Qianhui Wang, Yuanfeng Gao, Dilare Taiwaikuli, Huanhuan Ding, Jie Song, Xinchun Yang, Baopeng Tang, Xianhui Zhou

Department of Cardiac Pacing and Electrophysiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, People's Republic of China.Department of Cardiac Pacing and Electrophysiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, 830054, People's Republic of China. · pubmed

Paper

Abstract

Telomere length (TL) has been linked to mortality risk across various populations. However, its predictive value for mortality risk specifically in hypertensive adults remains unclear.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that DNA methylation-based telomere length is a stronger predictor of long-term all-cause mortality than quantitative polymerase chain reaction-based telomere length in hypertensive adults. This research is relevant as it explores the relationship between telomere length and mortality risk, which is a significant aspect of aging and longevity.

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