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RESEARCH PAPER / 2025-02-14

Angela M Tuckowski, Safa Beydoun, Elizabeth S Kitto, Ajay Bhat, Marshall B Howington, Aditya Sridhar, Mira Bhandari, Kelly Chambers, Scott F Leiser

Cellular and Molecular Biology Program, University of Michigan, Ann Arbor, United States.Cellular and Molecular Biology Program, University of Michigan, Ann Arbor, United States. · pubmed

Paper

Abstract

Flavin-containing monooxygenases (FMOs) are a conserved family of xenobiotic enzymes upregulated in multiple longevity interventions, including nematode and mouse models. Previous work supports that

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Research summary

The paper suggests that flavin-containing monooxygenases (FMOs) play a role in longevity interventions across different model organisms. The focus on FMOs and their upregulation in longevity interventions indicates a potential link to mechanisms of aging and lifespan extension.

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