Serum Growth Differentiation Factor 15 is Negatively Associated with Leukocyte Telomere Length.

Jie Yu, Yiwen Liu, Huabing Zhang, Fan Ping, Wei Li, Lingling Xu, Yuxiu Li

Department of Endocrinology, Key Laboratory of Endocrinology of National Health Commission, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730. · pubmed

Paper

Abstract

Telomere length(TL)and mitochondrial DNA copy number(mtDNAcn) are classic biomarker of aging. Recently, growth differentiation factor 15(GDF15) has attracted considerable attention as a vital component in the aging process.

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Research summary

The paper claims that higher levels of serum growth differentiation factor 15 are associated with shorter leukocyte telomere length. This research is relevant as it explores biomarkers associated with aging, specifically focusing on GDF15's role in the aging process, which could provide insights into the mechanisms of aging and potential interventions.

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