Association between sex steroid hormones and α-klotho: Results from the NHANES 2013-2016 and Mendelian randomization study.

Andong Guo, Pengcheng Chen, Jishuang Cao, Chenrui Wu, Sentai Ding

Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong, China.Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, Shandong, China. · pubmed

Paper

Abstract

This study aimed to explore the association and causal links between sex steroid hormones and the anti-aging protein α-Klotho, extending to investigate the mediation effects of potential mediators.

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Research summary

The study investigates the association between sex steroid hormones and the anti-aging protein α-Klotho, suggesting potential causal links. This research is relevant as it explores biological mechanisms that may underlie aging processes and could contribute to understanding longevity.

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