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RESEARCH PAPER / 2025-01-28

The multi-omics signatures of telomere length in childhood.

Congrong Wang, Dries S Martens, Mariona Bustamante, Rossella Alfano, Michelle Plusquin, Lea Maitre, John Wright, Rosemary R C McEachan, Johanna Lepeule, Remy Slama, Marina Vafeiadi, Leda Chatzi, Regina Grazuleviciene, Kristine B Gutzkow, Hector Keun, Eva Borràs, Eduard Sabidó, Angel Carracedo, Georgia Escarami, Augusto Anguita-Ruiz, Dolors Pelegrí-Sisó, Juan R Gonzalez, Martine Vrijheid, Tim S Nawrot

Centre for Environmental Health, Hasselt University, Hasselt, Belgium.Centre for Environmental Health, Hasselt University, Hasselt, Belgium. · pubmed

Abstract

Telomere length is an important indicator of biological age and a complex multi-factor trait. To date, the telomere interactome for comprehending the high-dimensional biological aspects linked to telomere regulation during childhood remains unexplored. Here we describe the multi-omics signatures associated with childhood telomere length.

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Research summary

The paper investigates the multi-omics signatures associated with telomere length in childhood. Understanding telomere length and its regulation during childhood could provide insights into biological aging processes and potential interventions for longevity.

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