Twelve-hour ultradian rhythmic reprogramming of gene expression in the human ovary during aging.

Lina Chen, Peigen Chen, Yun Xie, Jiayi Guo, Rouzhu Chen, Yingchun Guo, Cong Fang

Center of Reproductive Medicine, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China.Center of Reproductive Medicine, The Sixth Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510655, China. · pubmed

Paper

Abstract

The 12-h ultradian rhythm plays a crucial role in metabolic homeostasis, but its role in ovarian aging has not been explored. This study investigates age-related changes in 12-h rhythmic gene expression across various human tissues, with a particular focus on the ovary.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that age-related changes in 12-h rhythmic gene expression in the ovary can influence ovarian aging. This research explores a potential mechanism underlying aging processes, which is relevant to understanding longevity and age-related changes in reproductive health.

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