Association between gut microbiome profiles and host metabolic health across the life course: a population-based study.

Ruolin Li, Alexander Kurilshikov, Shuyue Yang, Julie A E van Oortmerssen, Arno van Hilten, Fariba Ahmadizar, Gennady Roshchupkin, Robert Kraaij, Liesbeth Duijts, Jingyuan Fu, M Kamran Ikram, Vincent W V Jaddoe, André G Uitterlinden, Fernando Rivadeneira, Maryam Kavousi, Alexandra Zhernakova, Carolina Medina-Gomez

Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands. · pubmed

Paper

Abstract

The human gut microbiome changes considerably over time. Previous studies have shown that gut microbiome profiles correlate with multiple metabolic traits. As disease development is likely a lifelong process, evidence gathered at different life stages would help gain a better understanding of this correlation. Therefore, we aim to investigate how the association of the gut microbiome and metabolic traits change over the lifespan.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that the association between gut microbiome profiles and metabolic traits varies across the lifespan. This research is relevant as it explores the relationship between gut health and metabolic processes, which are integral to understanding aging and potential interventions for age-related diseases.

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