Fracture characteristics of human cortical bone influenced by the duration of

Mei-Chun Lin, Praveer Sihota, Sofie Dragoun Kolibová, Imke A K Fiedler, Johannes Krug, Eva M Wölfel, Manuela Moritz, Maria Riedner, Benjamin Ondruschka, Mustafa Citak, Felix Klebig, Felix N von Brackel, Mahan Qwamizadeh, Katharina Jähn-Rickert, Björn Busse

Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, 22529 Hamburg, Germany.Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, 22529 Hamburg, Germany. · pubmed

Paper

Abstract

Advanced glycation end products (AGEs) accumulate in various tissues, including bone, due to aging and conditions like diabetes mellitus. To investigate the effects of AGEs on bone material quality and biomechanical properties, an

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper claims that advanced glycation end products (AGEs) negatively affect the material quality and biomechanical properties of human cortical bone. This research is relevant as it explores the impact of AGEs, which are associated with aging and age-related diseases, on bone health, potentially contributing to understanding the mechanisms of aging and longevity.

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