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RESEARCH PAPER / 2025-01-17

The associations of long-term physical activity in adulthood with later biological ageing and all-cause mortality - a prospective twin study.

Anna Kankaanpää, Asko Tolvanen, Laura Joensuu, Katja Waller, Aino Heikkinen, Jaakko Kaprio, Miina Ollikainen, Elina Sillanpää

Gerontology Research Center (GEREC), Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland. · pubmed

Abstract

The association between leisure-time physical activity (LTPA) and a lower risk of mortality is susceptible to bias from multiple sources. We investigated the potential of biological ageing to mediate the association between long-term LTPA and mortality and whether the methods used to account for reverse causality affect the interpretation of this association.

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Research summary

Long-term leisure-time physical activity is associated with reduced biological aging and lower all-cause mortality. This study is relevant as it explores the relationship between physical activity and biological aging, which is a key factor in longevity research.

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