Serum Nutrients, Periodontitis and Biological Ageing.

L M Nguyen, A V Tran, J P Kincheloe, J E Ebersole

Department of Biomedical Sciences, School of Dental Medicine, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.Department of Biomedical Sciences, School of Dental Medicine, University of Nevada, Las Vegas, Las Vegas, Nevada, USA. · pubmed

Paper

Abstract

Telomeres are nucleotide sequences found at the end of chromosomes, and their shortening is associated with chronological and biological ageing, oxidative stress and malnutrition. Shorter telomeres have been shown to be associated with periodontitis. Dietary nutrients are also influential factors in the aetiology and progression of periodontitis and other chronic inflammatory diseases. We tested the hypothesis that blood serum levels of folate, vitamin D, vitamin E, cis-β-carotene and/or β-cryptoxanthin are associated with telomere lengths and periodontitis and that these relationships are modified by factors that also affect periodontitis (e.g., age, sex, smoking, race/ethnicity).

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Research summary

The paper investigates the relationship between serum nutrient levels, telomere length, and periodontitis, which are all factors associated with biological aging. While it touches on aspects of aging and chronic inflammatory diseases, the focus is more on associations rather than addressing root causes or mechanisms of aging. The findings may contribute to understanding the interplay between nutrition and aging but do not present groundbreaking insights that could significantly advance the field of longevity research.

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