Multimodal phenotyping of successful cognitive aging.

Niklas Behrenbruch, Eóin N. Molloy, Svenja Schwarck, Beate Schumann‐Werner, Berta Garcia‐Garcia, Niklas Vockert, Barbara Morgado, Michael Rullmann, Anne Hochkeppler, Larissa Fischer, Kathrin Baldauf, Peter Schulze, Patrick Müller, Andrew W. Stephens, Marianne Patt, Andreas Schildan, Gusalija Behnisch, Constanze I. Seidenbecher, Björn H. Schott, Hermann Esselmann, Jens Wiltfang, Henryk Barthel, Osama Sabri, Michael C. Kreißl, Emrah Düzel, Anne Maass

Institute of Cognitive Neurology and Dementia Research (IKND), Otto‐von‐Guericke University, Magdeburg, GermanyInstitute of Cognitive Neurology and Dementia Research (IKND), Otto‐von‐Guericke University, Magdeburg, Germany · pubmed

Paper

Abstract

While some memory decline in old age is “normal”, there are some older individuals with maintained high cognitive performance. Using a multimodal approach including neuroimaging, fitness, genetic and questionnaire data (Figure 1A), we aimed to identify factors that are related to successful cognitive aging and whether these differ between sexes.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates factors associated with successful cognitive aging, which is pertinent to understanding the mechanisms of aging and longevity. However, it primarily focuses on correlational data rather than addressing root causes or mechanisms of aging itself. The findings may contribute to the field but do not represent a significant advancement or breakthrough.

Author of this paper? Send a correction.