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RESEARCH PAPER / 2025-01-10

Age‐related differences in the relationship between sleep quality and cortical thickness.

Hyun Kim, Yisha Zhang, Benjamin Huber, Elizabeth Rueppel, Terry E. Goldberg, Seonjoo Lee

Columbia University Irving Medical Center, New York, NY, USAColumbia University Irving Medical Center, New York, NY, USA · pubmed

Abstract

While the association between sleep quality and brain health is well established, the role of aging in this relationship is largely unknown. This study aimed to examine the interaction between sleep and age on cortical thickness using samples from large‐scale cohort studies. Age was examined in both linear and non‐linear (quadratic) terms, in order to determine the presence of critical age ranges that may exhibit more significant sleep‐related brain structural changes.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the relationship between sleep quality and cortical thickness in the context of aging, which is pertinent to understanding brain health as we age. However, while it contributes to the knowledge of how sleep may affect brain structure in older adults, it does not address root causes of aging or lifespan extension directly. Thus, its impact is solid but limited in the broader context of longevity research.

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