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RESEARCH PAPER / 2025-01-10

Association of lifestyle activities with cognitive function and Alzheimer’s disease CSF biomarkers: an examination of cognitively normal adults in the Stanford Aging and Memory Study (SAMS).

Olivia Lu, Elizabeth Mormino, Zihuai He, Valerie A Carr, Alexandra N. Trelle, Christina B. Young, America Romero, Hillary Vossler, Jennifer Park, Irina Anna Skylar‐Scott

Stanford University, Palo Alto, CA, USAStanford University, Palo Alto, CA, USA · pubmed

Abstract

It is increasingly clear that delaying the onset of Alzheimer’s disease (AD) dementia by several years can meaningfully lower its prevalence. The goal of the present study is to examine the relationship between lifestyle activities and cognition function as well as cerebrospinal fluid (CSF) biomarkers of AD to determine whether these activities can serve as protective factors for AD resistance and resilience.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper examines the relationship between lifestyle activities and cognitive function in the context of Alzheimer's disease, which is relevant to aging and age-related diseases. However, it primarily focuses on correlational findings rather than addressing the root causes of aging or providing novel interventions for lifespan extension. While it contributes to understanding factors that may influence cognitive health, its impact is limited as it does not present groundbreaking findings or transformative insights into aging mechanisms.

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