Longitudinal gene and protein expression changes associated with Mini‐Mental State Examination (MMSE) score in Hispanic/Latino population.

Rashedeh Roshani, Wanying Zhu, Elizabeth Frankel, Hung‐Hsin Chen, Miryoung Lee, Joseph B McCormick, Susan P Fisher‐Hoch, Heather M Highland, Kari E North, Jennifer Elizabeth Below

Vanderbilt University Medical Center, Nashville, TN, USAVanderbilt University Medical Center, Nashville, TN, USA · pubmed

Paper

Abstract

Studies suggest that approximately 60 to 70 percent of the variability observed in cognitive abilities during aging can be attributed to genetic factors. Therefore, investigating the longitudinal multiomics changes associated with alterations in cognitive measures, such as the Mini‐Mental State Examination (MMSE) score, is of utmost importance.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the relationship between gene and protein expression changes and cognitive abilities in a specific population, which is relevant to understanding the biological underpinnings of cognitive decline associated with aging. However, it primarily focuses on correlational findings rather than addressing the root causes of aging or proposing interventions for lifespan extension. Thus, while it contributes to the field, its impact is limited.

Author of this paper? Send a correction.