Nutritional specificity of frailty: from epidemiological and clinical evidence to potential mechanisms.

Laetitia Lengelé, Natasha A Grande de França, Philipe de Souto Barreto, Yves Rolland

Metabolism and Nutrition Research Group, Louvain Drug Research Institute, UCLouvain, Université catholique de Louvain, Sint-Lambrechts-Woluwe, Belgium.Metabolism and Nutrition Research Group, Louvain Drug Research Institute, UCLouvain, Université catholique de Louvain, Sint-Lambrechts-Woluwe, Belgium. · pubmed

Paper

Abstract

Considering the ageing of the population, age-related syndromes, such as frailty, are prominent. In this context, nutrition is a modifiable factor considered a key nonpharmacological approach to prevention and treatment. Yet, its contribution to the frailty pathophysiology is conflicting in the literature. This paper discusses the recent literature (January 2023-June 2024) on the implication of nutrition in frailty management.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper addresses the role of nutrition in managing frailty, which is a significant age-related syndrome. While it discusses potential mechanisms and recent literature, the focus remains on treatment rather than addressing the root causes of aging. Therefore, it contributes solidly to the understanding of frailty but does not present groundbreaking findings that would significantly advance the field of longevity research.

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