Association Between Maternal Prepregnancy and Pregnancy Body Mass Index and Children's Telomere Length: A Systematic Review and Meta-analysis.

Amir Hossein Lame-Jouybari, Mohammad Salar Fahami, Mahla Sadat Hosseini, Maryam Moradpour, Ali Hojati, Mahdieh Abbasalizad-Farhangi

Department of Community Nutrition, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, 5166614711, Iran.Department of Community Nutrition, Faculty of Nutrition, Tabriz University of Medical Sciences, Tabriz, 5166614711, Iran. · pubmed

Paper

Abstract

Telomeres maintain chromosome stability and mark cellular aging, and their shortening with age compromises genomic stability.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the association between maternal body mass index and children's telomere length, which relates to cellular aging and genomic stability. While it touches on aspects of aging through telomere biology, it primarily focuses on maternal health and its implications for offspring rather than addressing the root causes of aging or lifespan extension directly. Thus, while it contributes to the understanding of telomere dynamics, its impact on the broader field of longevity research is limited.

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