Integrating accelerometry, GPS, GIS and molecular data to investigate mechanistic pathways of the urban environmental exposome and cognitive outcomes in older adults: a longitudinal study protocol.
Abstract
Maintaining cognitive health in later life is a global priority. Encouraging individuals to make health behaviour changes, such as regular physical activity, and providing supportive urban environments can help maintain cognitive health, thereby preventing or delaying the progress of dementia and cognitive decline. However, the mechanistic pathways by which the urban environmental exposome influences cognitive health outcomes are poorly understood. The aim of this study is to use granular measures of the urban environment exposome (encompassing the built, natural and social environment) and physical activity to explore how these interact with a person's biology to ultimately influence cognitive health outcomes.
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Research summary
The paper investigates the relationship between urban environmental factors and cognitive health outcomes in older adults, which is pertinent to understanding aspects of aging and cognitive decline. However, it primarily focuses on observational and correlational studies rather than addressing the root causes of aging or proposing interventions that could lead to lifespan extension. The impact is limited as it provides solid research but does not significantly advance the field in a transformative way.
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