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RESEARCH PAPER / 2024-11-27

Alleviating D-Galactose-Induced Aging in Mice by Modulating Gut-Liver Axis Using

Shaoqi Shi, Xiaoxia Li, Feng Zhang, Zhengqiang Jiang, Jing Wang, Liang Zhao, Juan Chen, Xi Shu, Bing Fang, Ping Liu, Jingjing He, Shaoyang Ge, Fuqing Wang, Jie Guo, Yixuan Li, Jie Luo, Ran Wang

Key Laboratory of Functional Dairy, Department of Nutrition and Health, Co-Constructed by Ministry of Education and Beijing Government, China Agricultural University, Beijing 100190, China.Key Laboratory of Functional Dairy, Department of Nutrition and Health, Co-Constructed by Ministry of Education and Beijing Government, China Agricultural University, Beijing 100190, China. · pubmed

Abstract

Oxidative stress is closely linked to aging. Probiotics, whether viable or heat-inactivated, have shown antioxidant properties; however, their effect and mechanism of action in reducing oxidative stress during aging remains underexplored. This study examined the effects of viable and heat-inactivated

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the effects of probiotics on oxidative stress, which is a contributing factor to aging. By focusing on the gut-liver axis and its modulation, the study addresses a potential mechanism that could influence aging processes. However, the research appears to be more of a solid investigation into a specific aspect of aging rather than a groundbreaking discovery, thus limiting its overall impact on the field of longevity research.

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