Sex Differences in Metabolic Disorders of Aging and Obesity in People with HIV.

Jessica A Alvarez, Chin-An Yang, Victoria Ojuri, Kahsavyah Buckley, Brahmchetna Bedi, Joffi Musonge-Effoe, Adaiah Soibi-Harry, Cecile D Lahiri

Department of Medicine, Division of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA, USA.Department of Medicine, Division of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA, USA. · pubmed

Paper

Abstract

As advances in antiretroviral therapy for people with HIV (PWH) have prolonged lifespans, prevalence of aging and obesity related metabolic disorders have increased. The purpose of this review is to summarize recent research assessing sex differences in metabolic disorders among PWH, including weight gain/obesity, steatotic liver disease, insulin resistance/diabetes, dyslipidemia, bone loss/osteoporosis, and sarcopenia.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper addresses sex differences in metabolic disorders among people with HIV, which is relevant to aging as it discusses conditions that are prevalent in older populations. However, it primarily focuses on the symptoms and complications associated with aging and obesity rather than addressing the root causes of aging or lifespan extension. Thus, while it contributes to understanding specific health issues in an aging demographic, its overall impact on the field of longevity research is limited.

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