Hippocampal neurogenesis in adult primates: a systematic review.

Thomas Elliott, Kathy Y Liu, Jemma Hazan, Jack Wilson, Hemisha Vallipuram, Katherine Jones, Jansher Mahmood, Guy Gitlin-Leigh, Robert Howard

East London NHS Foundation Trust, London, UK. [email protected] London NHS Foundation Trust, London, UK. [email protected]. · pubmed

Paper

Abstract

It had long been considered that no new neurons are generated in the primate brain beyond birth, but recent studies have indicated that neurogenesis persists in various locations throughout the lifespan. The dentate gyrus of the hippocampus is of particular interest due to the postulated role played by neurogenesis in memory. However, studies investigating the presence of adult hippocampal neurogenesis (AHN) have reported contradictory findings, and no systematic review of the evidence has been conducted to date. We searched MEDLINE, Embase and PsycINFO on 27

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper addresses adult hippocampal neurogenesis, which is relevant to understanding brain health and cognitive function in aging. However, while it contributes to the knowledge of neurogenesis in primates, it does not directly tackle the root causes of aging or lifespan extension. The systematic review may provide solid insights but lacks groundbreaking findings that would significantly advance the field of longevity research.

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