Mendelian randomization analyses support causal relationships between gut microbiome and longevity.

Shu Chen, Wei Chen, Xudong Wang, Sheng Liu

Department of Pathology, The Seven Affiliated Hospital, Sun Yat-Sen University, Shenzhen, 518107, Guangdong, China. · pubmed

Paper

Abstract

Gut microbiome plays a significant role in longevity, and dysbiosis is indeed one of the hallmarks of aging. However, the causal relationship between gut microbiota and human longevity or aging remains elusive.

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the causal relationships between the gut microbiome and longevity, which aligns with the exploration of root causes of aging. While it presents solid research, the findings may not significantly advance the field or provide groundbreaking insights, thus warranting a moderate impact score.

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