Impact of Alcohol Consumption on Lifespan: a Mendelian randomization study in Europeans.

Zhu Liduzi Jiesisibieke, C Mary Schooling

School of Public Health, The University of Hong Kong Li Ka Shing Faculty of Medicine, 7 Sassoon Road, Pokfulam, Hong Kong, Hong Kong.School of Public Health, The University of Hong Kong Li Ka Shing Faculty of Medicine, 7 Sassoon Road, Pokfulam, Hong Kong, Hong Kong. · pubmed

Paper

Abstract

Alcohol is widely used but recognized as a risk factor for several adverse health outcomes based on observational studies. How alcohol affects lifespan remains controversial, with no trial to make such an assessment available or likely. We conducted a Mendelian randomization (MR) to assess the effect of alcohol on lifespan in men and women, including a possible role of smoking and education. Strong (p < 5e

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Research summary

The paper investigates the relationship between alcohol consumption and lifespan using Mendelian randomization, which is a relevant approach in longevity research. However, while it addresses an important public health issue, the findings are likely to contribute incrementally to the existing body of knowledge rather than providing groundbreaking insights into the root causes of aging or lifespan extension.

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