Increased hydrogen sulfide turnover serves a cytoprotective role during the development of replicative senescence.

Anna Kieronska-Rudek, Kelly Ascencao, Stefan Chlopicki, Csaba Szabo

Chair of Pharmacology, Department of Science and Medicine, University of Fribourg, Fribourg, Switzerland; Jagiellonian University, Jagiellonian Centre for Experimental Therapeutics (JCET), Cracow, Poland.Chair of Pharmacology, Department of Science and Medicine, University of Fribourg, Fribourg, Switzerland; Jagiellonian University, Jagiellonian Centre for Experimental Therapeutics (JCET), Cracow, Poland. · pubmed

Paper

Abstract

The mammalian gasotransmitter hydrogen sulfide (H

The following analysis is generated by AI and may contain errors. It is separate from the authors’ abstract and is not peer review.

Research summary

The paper investigates the role of hydrogen sulfide turnover in the context of replicative senescence, which is a process associated with aging. By focusing on a potential cytoprotective mechanism, it addresses a biological aspect related to the aging process rather than merely treating age-related diseases. However, while the findings may contribute to our understanding of cellular aging, they do not present a groundbreaking advance in the field, hence the moderate impact score.

Author of this paper? Send a correction.