Metabolic kinetics and muscle and brain health markers in older adults, and the role of age and presence of chronic morbidities: A large cross-sectional cohort study.

Minchae C Kang, Nicolaas E P Deutz, Sarah K Kirschner, Mariëlle P K J Engelen

Center for Translational Research in Aging & Longevity, Texas A&M University, College Station, TX, USA.Center for Translational Research in Aging & Longevity, Texas A&M University, College Station, TX, USA. · pubmed

Paper

Abstract

Older adults are at risk for muscle and cognitive function decline during advanced aging, but the underlying metabolic mechanisms and the role of aging-associated chronic morbidities remain unclear. In the present study, we examined whether protein and amino acid kinetics in older adults with and without chronic morbidities are different when 50-70 and 70-90 of age and related to markers of muscle and brain health declines.

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Research summary

The paper investigates metabolic mechanisms related to muscle and cognitive decline in older adults, which is pertinent to understanding aging processes. However, it primarily focuses on associations rather than addressing root causes or interventions that could extend lifespan or mitigate aging effects. The findings may contribute to the field but do not represent a significant advancement or breakthrough.

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