Higher FSH Level Is Associated With Increased Risk of Incident Hip Fracture in Older Adults, Independent of Sex Hormones.

Eileen H Koh, Susan K Ewing, Sigurdur Sigurdsson, Vilmundur Gudnason, Trisha F Hue, Eric Vittinghoff, Claes Ohlsson, Åsa Tivesten, Louise Grahnemo, Tony Yuen, Mone Zaidi, Clifford J Rosen, Ann V Schwartz, Anne L Schafer

Department of Medicine, University of Washington, Seattle, WA 98195, USA. · pubmed

Paper

Abstract

Higher levels of FSH are associated with bone loss among women during the perimenopausal transition and among older men, independent of estradiol and testosterone levels, but whether higher FSH is an independent fracture risk factor is unknown.

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Research summary

Higher levels of FSH are associated with an increased risk of hip fractures in older adults, independent of sex hormones. This study addresses a potential risk factor for age-related bone loss, which is relevant to understanding and mitigating the effects of aging on skeletal health.

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