Contextualizing aging clocks and properly describing biological age.
Abstract
Usage of the phrase "biological age" has picked up considerably since the advent of aging clocks and it has become commonplace to describe an aging clock's output as biological age. In contrast to this labeling, biological age is also often depicted as a more abstract concept that helps explain how individuals are aging internally, externally, and functionally. Given that the bulk of molecular aging is tissue-specific and aging itself is a remarkably complex, multifarious process, it is unsurprising that most surveyed scientists agree that aging cannot be quantified via a single metric. We share this sentiment and argue that, just like it would not be reasonable to assume that an individual with an ideal grip strength, VO
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Research summary
The paper discusses the concept of biological age in the context of aging clocks, which is relevant to understanding the complexities of aging and its measurement. However, it primarily focuses on the conceptual framework rather than presenting novel findings or methodologies that could significantly advance the field of longevity research. Thus, while it contributes to the discourse on biological age, its impact is limited.
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