Melatonin protects against sarcopenia in middle-aged mice.

Fei Fang, Ping Yu, Xiaoying Sun, Zhixing Shen, Fan Zhang, Jianwei Sun

Department of Geriatrics, Huzhou Third Municipal Hospital, The Affiliated Hospital of Huzhou University, Huzhou City, Zhejiang Province, PR China. · pubmed

Paper

Abstract

Sarcopenia is a common age-related disease. Melatonin (MEL) is an age-related endocrine hormone, which displays a crucial role in resisting oxidative stress during aging. Importantly, the antioxidant properties of MEL can be mediated by mitochondria.

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Research summary

Melatonin administration protects against sarcopenia in middle-aged mice. The study addresses a specific age-related condition and explores a potential intervention that may mitigate aspects of aging, aligning with longevity research goals.

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